Self-paced course

Code of Life - When Computer Science Meets Genetics

Offered by Dr.-Ing. Matthieu-P. Schapranow

The listed learning units belong to the course Code of Life - When Computer Science Meets Genetics . Do you want to access all course content?

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Week 1: History of DNA and core components of cells

Back to school: let's test your current biology background. We will start with a concrete real-world use case from medicine to explain core components of human cells, their function, and how they interact.

Welcome to Week 1

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1.1 Discovery of the Human Genome

Video

1.1 Discovery of the Human Genome

Self-test

1.2 Real-world Use Case: Oncology

Video

1.2 Real World Use-Case: Oncology

Self-test

1.3 Architecture: Components of Cells

Video

1.3 Architecture: Components of Cells

Self-test

1.4 Data Storage: Components of DNA and RNA

Video

1.4 Data Storage: Components of DNA and RNA

Self-test

1.5 Lifecycle Management: Replication

Video

1.5 Lifecycle Management: Replication

Self-test

1.6 Compiling the Code: Transcription and Translation

Video

1.6 Compiling the Code: Transcription and Translation

Self-test

1.7 Bugs: Genetic Changes

Video

1.7 Bugs: Genetic Changes

Self-test

Course Start Survey

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Learning Material

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Weekly Assignment Week 1

Graded Test

Week 2: Processing and analyzing of genetic data

How to turn genetic raw data into meaningful information is the content of this week. Specific data processing steps are required prior to interpreting genetic data. In this week we will address specific algorithms, IT methods, and processes to assess genetic data. Furthermore, you will gain hands-on experience in analyzing selected genetic variants and evaluating their relevance.

Welcome to Week 2

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2.1 Digital Transformation - From DNA and RNA to Data

Video

2.1 Digital transformation: From DNA and RNA to Data

Self-test

2.2 Reconstruct the Genome - Alignment

Video

2.2 Reconstruct the genome: Alignment

Self-test

2.3 Identifying Changes - Variant Calling

Video

2.3 Identifying Changes - Variant Calling

Self-test

2.4 Genetic Annotations

Video

2.4 Genetic Annotations

Self-test

2.5 Reproducible Research - Graphical Pipeline Modeling

Video

2.5 Reproducible Research - Graphical Pipeline Modeling

Self-test

2.6 Reproducible Research - Pipeline Execution

Video

2.6 Reproducible Research – Pipeline execution

Self-test

2.7 Solve the Puzzle

Video

2.7 Solve the Puzzle

Self-test

2.8 Additional Information on the Final Exam

Video

Learning Material

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Weekly Assignment Week 2

Graded Test

Week 3: Online Q&A and final exams

In this week you will have the chance to discuss any open questions with the teaching team using our online tools. Furthermore, you will have to complete your final exams of the course in this week. We also encourage you to join our "I like, I wish" discussion providing your feedback of the course.

Important information on the final test

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Genome Browser and Medical Knowledge Cockpit

Video

Genome Browser and Medical Knowledge Cockpit - Accessing the tools

Exercise

Genome Browser and Medical Knowledge Cockpit - Answer the questions

Self-test

Final Test - Part 1 - Finding the Correct Position on the Genome Browser

Graded Exercise

Final Test - Part 2 - Analyzing Genetic Variants with the Genome Browser

Graded Test

Final Test - Part 3 - Tapping into medical research with the Medical Knowledge Cockpit

Graded Test